The Plasmablasts in Castleman Disease
نویسندگان
چکیده
منابع مشابه
The plasmablasts in Castleman disease.
To the Editor In their article, Hsi et al 1 described the broad spectrum of histopathologic features of Castleman disease (CD). We would like to report one additional peculiar case, rich in human herpesvirus-8 (HHV-8)–infected plasmablasts (PBs), which we recently observed in our institution. The normal PB is a short-lived, very mobile B cell that can secrete antibodies but retains characterist...
متن کاملCastleman disease
Castleman and Towne described a disease presenting as a mediastinal mass resembling thymoma. It is also known as "giant lymph node hyperplasia", "lymph node hamartoma", "angiofollicular mediastinal lymph node hyperplasia", and "angiomatous lymphoid hyperplasia". The pathogenesis is unknown, but the bulk of evidence points toward faulty immune regulation, resulting in excessive B-lymphocyte and ...
متن کاملIntrathoracic Castleman disease.
AIM To analyze patients with Castleman disease who were diagnosed by surgery. MATERIALS AND METHODS We retrospectively investigated the postoperative pathological records of operations performed between January 1992 and December 2012 in our hospital. Files of 19 patients with the diagnosis of Castleman disease were analyzed. RESULTS There were 13 male and 6 female patients with a mean age o...
متن کاملPeripancreatic Castleman disease.
CONTEXT Castleman disease or giant lymph node hyperplasia is a rare disorder of the lymphoid tissue, usually occurring in the mediastinum. We report a case of localized peripancreatic plasma cell type Castleman disease, which is an unusual site. CASE REPORT A 45-year-old woman with a history of mild epigastric pain radiating to the back for the previous year was admitted and her physical exam...
متن کاملCastleman disease-associated diffuse parenchymal lung disease
Intrathoracic involvement is common in Castleman disease (CD), but CD-associated diffuse parenchymal lung disease (DPLD) is rare and not well-reported.We conducted a retrospective analysis of 262 CD patients with a definite pathological diagnosis who were hospitalized between 1999 and 2015.Twenty-two CD patients had DPLD based on chest computed tomography (CT) scans. Among them, 9 were male and...
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ژورنال
عنوان ژورنال: American Journal of Clinical Pathology
سال: 2013
ISSN: 1943-7722,0002-9173
DOI: 10.1309/ajcp5mcr0etaakzk